Prostate Cancer: Treatment and Precautions

Dr. Ankit Goel, Head of the Department – Urology, Andrology & Uro-Oncology at MASSH Hospitals, Delhi

Prostate cancer cases are on the rise in India, becoming one of the top ten leading cancers in the country. This increasing trend is particularly concerning, as it is not confined to older men; cases are increasingly reported among men in their 40s and 50s. A recent study by The Lancet projects that the number of prostate cancer cases in India will double by 2040. Prostate cancer can often be asymptomatic in its early stages. However, some common symptoms to watch out for include difficulty in urinating, blood in urine or semen, pelvic pain.

Innovative Imaging Techniques

For men with recurrent prostate cancer, new imaging techniques like PSMA-PET scans are proving invaluable. These scans utilize a protein, PSMA, which is abundant in prostate cells, to identify even the smallest cancerous deposits. The FDA has approved two compounds for use in PSMA-PET imaging, helping doctors detect and treat cancer more effectively at earlier stages.

Emerging Treatments for Prostate Cancer

Treatment options for prostate cancer continue to evolve. Hormone therapy has seen significant advancements, with new drugs like enzalutamide (Xtandi) and abiraterone (Zytiga) improving outcomes for men with advanced or metastatic prostate cancer. Additionally, PARP inhibitors and immunotherapy are showing promise, particularly for cancers with specific genetic characteristics.

Precautions

To reduce the risk of prostate cancer and improve outcomes, men should prioritize regular screenings, especially those over 50 or with a family history of the disease. Maintaining a healthy lifestyle, including a balanced diet rich in fruits, vegetables, and antioxidants, staying physically active, and avoiding smoking and excessive alcohol can lower risk factors. High-risk individuals should discuss advanced imaging and biopsy techniques with their healthcare providers to ensure accurate detection and avoid overtreatment. Regular follow-ups and proactive management of side effects are crucial for those undergoing or post-treatment, helping maintain quality of life and detect any recurrence early.